Chronology of Ancient Persia 559-530 BC Reign of Cyrus the Great 530-522 BC Reign of Cambyses 521-485 BC Reign of Darius 499-493 BC The Ionian Revolt 490 BC Attempts to conquer the Greek mainland The Battle of Marathon 485-465 BC Reign of Xerxes 480 BC Battle of Thermopylae Battle of Salamis 479 BC Battle of Plataea Battle of Mycale 465-424 BC Reign of Artaxerxes I 424-404 BC Reign of Xerxes II 404-358 BC Reign of Artaxerxes II 358-338 BC Reign of Artaxerxes III 336-330 BC 334 BC 333 BC 331 BC Reign of Darius III Battle of Granicus Battle of Issus Battle of Guagamela 330 BC Alexander the Great conquers the Persian Empire 320-141 BC The Seleucid Period 250 BC- AD 225 The Parthian Empire 224-642 AD The Sassanian Dynasty